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The brain itself feels no pain—it has no pain receptors. Which is ironic, given how much it causes.

✓ TRUE FACT
Brain tissue lacks nociceptors, so the brain itself can’t “feel” pain. Headaches come from pain-sensitive tissues around it—meninges, blood vessels, scalp, sinuses, and nerves. That’s why brain surgery can sometimes be done with the patient awake.

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The brain itself feels no pain—it has no pain receptors. Which is ironic, given how much it causes. | SmartAss Facts